DANISH BIO – DANSK BIOTEK organizes four major plenary meetings for our members throughout the year to increase our members' knowledge regarding specific biotech topics and to facilitate networking. The events usually take place in February, May, September and November.

We also organize approximately four "saloon" meetings annually. They are small, intimate, "meet the expert" meetings with typically 6-20 participants advocating more in-depth discussion and knowledge-sharing on specific themes.

16 Oct 2023

Y-mAbs Announces Publication in Cancers

Naxitamab-based chemo-immunotherapy significantly improves long-term outcomes when administered early during the course of treatment
NEW YORK, Oct. 16, 2023 (GLOBE NEWSWIRE) — Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel, antibody-based therapeutic products for the treatment of cancer, today announced the publication of naxitamab-based chemoimmunotherapy in patients with chemoresistant high-risk neuroblastoma (“HR-NB”) in the journal Cancers.

“The publication in Cancers further validates the utilization of naxitamab early during the course of treatment for patients with high-risk neuroblastoma,” said Thomas Gad, Founder, President and Interim Chief Executive Officer. “In this study, early administration of naxitamab-based chemo-immunotherapy was shown to significantly improve long-term outcomes, addressing an important unmet need in the current treatment paradigm for this critical patient group.”

Approximately 50% of HR-NB patients are unable to achieve a complete response (“CR”) or very good partial response (“VGPR”) at the end of induction (“EOI”) and have poor long term outcomes. This analysis investigated the combination of humanized anti-GD2 mAb naxitamab (“Hu3F8”), irinotecan (“I”), temozolomide (“T”), and sargramostim (“GM-CSF”)—HITS—in patients with HR-NB who did not achieve a CR/VGPR to induction. Cycles were administered 3-5 weeks apart and the primary endpoint was overall response rate (CR + partial response (“PR”)).

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